SARS-CoV-2 infection and thyroid dysfunction in children

The problem of thyroid dysfunction related to SARS-CoV-2 infection remains unclear in children. Therefore, the study aimed reveal interrelationship between and COVID-19 severity­ as well determine optimal cut-off values for screening disorders A total number 90 children aged from 1 month 17 years were involved study. Patients with known disease not recruited research. panel was assessed all participants that included: free triiodothyronine (FT3), thyroxine (FT4), thyroid-stimulating hormone (TSH) anti-thyroid peroxidase (ATPO) antibodies. Statistical analysis done using computer software Statistica 13.0. Research has revealed euthyroid sick syndrome (ESS) 14.10% infected more often among patients severe multisystem inflammatory (33.33%) compared mild course (6.67%) moderate severity (8.89%) (P < 0.05). Significant correlation relationships next – FT3 erythrocyte sedimentation rate (ESR) (rs = -0.22; P 0.05); C-reactive protein (CRP) -0.33; procalcitonin -0.43; ESS determination revealed: ESR 18.5 mm/h (AUC 0.803); CRP 11.5 mg/l 0.763); ferritin 84.8 ng/ml 0.733). Results suggest pediatricians should pay attention endocrine disruptions by Keywords: COVID-19, children, markers